[学术文献] Effects of dietaryHermetia illucensmeal inclusion on cecal microbiota and small intestinal mucin dynamics and infiltration with immune cells of weaned piglets 进入全文
Web of Science
Background The constant interaction between diet and intestinal barrier has a crucial role in determining gut health in pigs.Hermetia illucens(HI) meal (that represents a promising, alternative feed ingredient for production animals) has recently been demonstrated to influence colonic microbiota, bacterial metabolite profile and mucosal immune status of pigs, but no data about modulation of gut mucin dynamics are currently available. The present study evaluated the effects of dietary HI meal inclusion on the small intestinal mucin composition of piglets, as well as providing insights into the cecal microbiota and the mucosal infiltration with immune cells. Results A total of 48 weaned piglets were randomly allotted to 3 dietary treatments (control diet [C] and 5% or 10% HI meal inclusion [HI5 and HI10], with 4 replicate boxes/treatment and 4 animals/box) and slaughtered after 61 days of trial (3 animals/box, 12 piglets/diet). The cecal microbiota assessment by 16S rRNA amplicon based sequencing showed higher beta diversity in the piglets fed the HI-based diets than the C (P < 0.001). Furthermore, the HI-fed animals showed increased abundance ofBlautia,Chlamydia,Coprococcus,Eubacterium,Prevotella,Roseburia, unclassified members of Ruminococcaceae,RuminococcusandStaphylococcuswhen compared to the C group (FDR < 0.05). The gut of the piglets fed the HI-based diets showed greater neutral mucin percentage than the C (P < 0.05), with the intestinal neutral mucins of the HI-fed animals being also higher than the sialomucins and the sulfomucins found in the gut of the C group (P < 0.05). Furthermore, the piglets fed the HI-based diets displayed lower histological scores in the jejunum than the other gut segments (ileum [HI5] or ileum and duodenum [HI10],P < 0.05). Conclusions Dietary HI meal utilization positively influenced the cecal microbiota and the small intestinal mucin dynamics of the piglets in terms of selection of potentially beneficial bacteria and preservation of mature mucin secretory architecture, without determining the development of gut inflammation. These findings further confirm the suitability of including insect meal in swine diets.
[学术文献] Effects of long-term feeding diets supplemented with Lactobacillus reuteri 1 on growth performance, digestive and absorptive function of the small intestine in pigs 进入全文
Web of Science
This study aimed to investigate the effects of long-term feeding diets supplemented with antibiotics and Lactobacillus reuteri 1 (LR1) on growth performance, intestinal digestion and absorption in pigs. The results showed that both LR1 and the antibiotics increased body weight of the piglets after 42-d (P < 0.05), and showed a tendency to promote growth performance in growing-finishing pigs. LR1 significantly improved jejunal and ileal mucosal morphology and increased expression of jejunal glucosidase and ileal cholecystokinin, digestive enzymes and nutrient transporters. The antibiotics decreased jejunal lactase, BO + AT1, FATP1, GLUT2, ileal y + LAT1, and GLUT2 (P < 0.05). LR1 stimulated protein synthesis of ileal mucosa rather than jejunal mucosa compared to control and antibiotic groups (P < 0.05). In conclusion, LR1 could be an alternative to antibiotics as a growth promoter that improves mucosal morphology, synthesis and secretion of cholecystokinin and digestion and absorption of small intestine.
New high-protein DDGS has greater amino acid digestibility and more metabolizable energy than de-oiled DDGS but has reduced phosphorus digestibility. With a greater ability to upcycle ethanol co-products into animal feed ingredients, companies are creating custom products and partnering with University of Illinois researchers to test for quality and digestibility. In a recent study published in the Journal of Animal Science, University of Illinois researchers showed that a new high-protein dried distillers grains with solubles (DDGS) product from Marquis Energy has greater energy and protein digestibility than conventional DDGS, according to an announcement from the university.