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GIGANTEA gates gibberellin signaling through stabilization of the DELLA proteins in Arabidopsis

GIGANTEA通过稳定拟南芥中的DELLA蛋白来控制赤霉素的信号传递

关键词:
来源:
PNAS期刊
全文链接1:
http://agri.ckcest.cn/topic/downloadFile/2a3f6aed-7fde-44bb-90ce-da05b3fbdfb5
全文链接2:
https://www.pnas.org/content/early/2019/10/08/1913532116
类型:
学术文献
语种:
英语
原文发布日期:
2019-10-09
摘要:
Circadian clock circuitry intersects with a plethora of signaling pathways to adequately time physiological processes to occur at the most appropriate time of the day and year. However, our mechanistic understanding of how the clockwork is wired to its output is limited. Here we uncover mechanistic connections between the core clock component GIGANTEA (GI) and hormone signaling through the modulation of key components of the transduction pathways. Specifically, we show how GI modulates gibberellin (GA) signaling through the stabilization of the DELLA proteins, which act as negative components in the signaling of this hormone. GI function within the GA pathway is required to precisely time the permissive gating of GA sensitivity, thereby determining the phase of GA-regulated physiological outputs.
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