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Data from: Divergence in DNA photorepair efficiency among genotypes from contrasting UV radiation environments in nature
负责人:
关键词:
Ultraviolet radiation Daphnia Photolyase Photoenzymatic repair Photoreactivation Adaptation
摘要:
on the presence of visible and UV-A light wavelengths necessary for photoenzymatic repair of DNA damage, a repair pathway widely shared across the tree of life
Data from: Long term effects of superoxide and DNA repair on lizard telomeres
负责人:
关键词:
Telomeres;Ctenophorus pictus;long term effects;DNA damage\/repair;reactive oxygen species;Holocene;lizards
摘要:
), but superoxide effects on telomeres are counteracted by DNA repair as revealed by 8-hydroxy-2’-deoxyguanosine assays. We conclude that reactive oxygen species
Data from: Competence increases survival during stress in Streptococcus pneumoniae.
负责人:
关键词:
competition;Sex;Selection - Experimental;Adaptation
摘要:
of this distinction in the naturally competent species Streptococcus pneumoniae, focussing specifically on predictions of the DNA-for-repair hypothesis. We confir
Data from: A trade-off between oxidative stress resistance and DNA repair plays a role in the evolution of elevated mutation rates in bacteria
负责人:
关键词:
Escherichia coli;trade-off;Pseudomonas aeruginosa;Evolution;mutator;Oxidative stress;P. aeruginosa
摘要:
ween the fidelity of DNA repair and hydrogen peroxide resistance. We demonstrate that the biochemical mechanism underlying this trade-off in the case of mutS
Data from: Temperature effects on life-history trade-offs, germline maintenance and mutation rate under simulated climate warming
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关键词:
Life history;environmental change;trade-off;Adaptation;mutation rate;Phenotypic Plasticity
摘要:
. This suggests that stress-induced mutation rates, in unicellular and multicellular organisms alike, can result from compromised germline DNA repair in low
Data from: Rev7 and 53BP1/Crb2 prevent RecQ helicase-dependent hyper-resection of DNA double-strand breaks
负责人:
关键词:
live-cell microscopy;end resection;Schizosaccharomyces pombe;DNA repair;DNA double-strand break
摘要:
Poly(ADP ribose) polymerase inhibitors (PARPi) target cancer cells deficient in homology-directed repair of DNA double-strand breaks (DSBs
Data from: ATRX promotes maintenance of herpes simplex virus heterochromatin during chromatin stress
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关键词:
摘要:
is uniquely required for heterochromatin maintenance during chromatin stress. These results argue that the initial formation and the subsequent maintenance
Data from: The induction of the fibroblast extracellular senescence metabolome is a dynamic process
负责人:
关键词:
metabolomics;senescence;Ageing;Homo Sapiens;p16INK4A;Holocene
摘要:
accumulate outside senescent fibroblasts independently of cell cycle arrest, repairable DNA breaks and cell size (the extracellular senescence metabolome
Data from: Landscape of tumor mutation load, mismatch repair deficiency, and PD-L1 expression in a large patient cohort of gastrointestinal cancers
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关键词:
摘要:
own to correlate with tumor mutation load (TML), mismatch repair deficiency status (dMMR), and programmed cell death-ligand 1 (PD-L1) expression. Herein, we attempt
Data from: The impacts of inbreeding, drift, and selection on genetic diversity in captive breeding populations
负责人:
关键词:
docility;pedigree;Captive Populations;Mitochondrial DNA;Holocene;microsatellite;mean kinship;Peromyscus leucopus;Adaptation
摘要:
The goal of captive breeding programs is often to maintain genetic diversity until reintroductions can occur. However, due in part to changes tha

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