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Data from: Risky behaviors and Parkinson’s disease: a Mendelian randomization study
负责人:
关键词:
causal inference;Risk factors in epidemiology; 59 Risk factors in epidemiology; 165 Parkinson's disease\/Parkinsonism;Mendelian randomization;Parkinson's disease \/ Parkinsonism;Smoking
摘要:
Objective: To examine causal associations between risky behavior phenotypes on Parkinson’s disease using a Mendelian randomization approach. Methods
Data from: Frequency and distribution of 152 genetic disease variants in over 100,000 mixed breed and purebred dogs
负责人:
Donner, Jonas
关键词:
dog canine Mendelian disease genotypes panel screening
摘要:
ng. Limited data on frequencies of genetic disease variants across breeds exists, and the disease heritage of mixed breed dogs remains poorly explored to dat
Data from: Relative effects of LDL-C on ischaemic stroke & coronary disease: a Mendelian randomization study
负责人:
关键词:
Risk factors in epidemiology;Stroke prevention;Cardiovascular disease;Mendelian randomization;Cholesterol
摘要:
t for coronary heart disease (CHD) using a Mendelian randomization approach. Methods: We undertook a two-sample Mendelian randomization, based on summary data, to estimate the causal
Data from: Molecular insights into genome-wide association studies of chronic kidney disease-defining traits
负责人:
关键词:
RNA sequencing;GWAS;Homo Sapiens;Chronic kidney disease;gene expression
摘要:
Genome-wide association studies (GWAS) have identified >100 loci of chronic kidney disease-defining traits (CKD-dt). Molecular mechanisms underlying
Data from: Population-specific genetic modification of Huntington's disease in Venezuela
负责人:
关键词:
摘要:
Modifiers of Mendelian disorders can provide insights into disease mechanisms and guide therapeutic strategies. A recent genome-wide association (GWA
Data from: Direct-to-consumer DNA testing of 6,000 dogs reveals 98.6-kb duplication associated with blue eyes and heterochromia in Siberian Huskies
负责人:
关键词:
Pigmentation;GWAS;Canis lupus familiaris;canine
摘要:
singly complex traits, behaviors, and disease by including many thousands of individuals in genome-wide association studies (GWAS). The promise of consumer genomic data
Data from: Whole genome sequencing and rare variant analysis in essential tremor families
负责人:
关键词:
Essential tremor;Susceptibility Gene;calcium channel;copy number variants;Homo Sapiens;rare variants;SLIT3;families;axon guidance;risk factor;whole genome sequencing;CACNA1G
摘要:
) is likely to be of value in understanding a large proportion of ET with Mendelian and complex disease inheritance patterns. In ET famili
Data from: Combining GWAS and RNA-seq approaches for detection of the causal mutation for hereditary junctional epidermolysis bullosa in sheep
负责人:
关键词:
Junctional Epidermolysis Bullosa aplasia cutis congenita integrin beta-4 sheep association mapping whole skin transcriptomic analysis
摘要:
, as an efficient approach to detect the causal mutation for a Mendelian disease. Junctional epidermolysis bullosa is a recessive genodermatosis that manifests with neonatal
Data from: Searching for the bull's-eye: agents and targets of selection vary among geographically disparate cyanogenesis clines in white clover
负责人:
关键词:
Cline Ecological Genetics Adapation Population Genetics Drought Tolerance Plant-Animal Interactions
摘要:
e adaptation. White clover is polymorphic for cyanogenesis (HCN release with tissue damage), and climate-associated cyanogenesis clines have evolved throug

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