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Data from: Deconstruction of an African folk medicine uncovers a novel molecular strategy for therapeutic potassium channel activation
负责人:
关键词:
Mallotus oppositifolius;KCNQ1;antiarrhythmic;potassium channel;Ethnobotany
摘要:
d folk medicine of an important human Kv channel and uncover novel molecular approaches for therapeutic modulation of potassium channel activity.
Data from: Expression and function of ATP-dependent potassium channels in zebrafish islet ?-cells
负责人:
关键词:
beta cell;insulin;Danio rerio;Fish;channel;ATP
摘要:
ATP-sensitive potassium channels (KATP channels) are critical nutrient sensors in many mammalian tissues. In the pancreas, KATP channels ar
Data from: Independent acquisition of sodium selectivity in bacterial and animal sodium channels
负责人:
关键词:
Bacterial sodium channels Ancestral state reconstruction Phylogeny
摘要:
electrical signals into cellular signals, respectively, both have the four-domain architecture, whereas voltage-gated potassium channels (Kv) have only one domain
Data from: Trans-toxin ion-sensitivity of charybdotoxin-blocked potassium-channels reveals unbinding transitional states
负责人:
关键词:
protein unbinding;Shaker Kv-channels;Charybdotoxin;Xenopus;Transition State;protein-protein interaction;protein wobbling
摘要:
s. Charybdotoxin (CTX), a peptide from the Leiurus scorpion venom, blocks voltage-gated K+-channels in a unique example of binding/unbinding simplicity. CTX plugs
Data from: Na+/K+‐ATPase gene duplications in clitellate annelids are associated with freshwater colonization
负责人:
Horn, Kevin M.
关键词:
Adaptation Genomics Molecular evolution Phylogenetics
摘要:
H. robusta contains many more copies (12) of the sodium-potassium pump alpha subunit (Na+/K+-ATPase) gene than does the marine polychaete C. telata
Data from: Hypothesised diprotomeric enzyme complex supported by stochastic modelling of Palytoxin-induced Na/K pump channels
负责人:
关键词:
Palytoxin;Na\/K Pump;Probabilistic Model;Statistical Model Checker
摘要:
, its mechanism is not completely understood. We propose the use of the Statistical Model Checker to investigate palytoxin-induced Na+/K+ pump channels. We modelled
Data from: Convergence of ion channel genome content in early animal evolution
负责人:
关键词:
Ancestral Genome Reconstruction ASIC/ENaC Cys-loop receptor Ionotropic Glutamate Receptor Potassium Channel
摘要:
. Here, we use ancestral gene content reconstruction to track the timing of gene family expansions for the major families of ion-channel proteins tha
Data from: De novo transcriptome assembly for the lobster Homarus americanus and characterization of differential gene expression across
负责人:
关键词:
transcriptome RNA-Seq gene expression central pattern generation locomotion neuronal differentiation lobster nervous system CNS heart
摘要:
kainite family glutamate receptors, inward-rectifying K+ (IRK) channels, and transient receptor potential (TRP) A family channels, across central pattern gene
Data from: Phylogenetically driven sequencing of extremely halophilic archaea reveals strategies for static and dynamic osmo-response
负责人:
关键词:
摘要:
ng the proton gradient as an energy source, and potassium loss during downshock is via a combination of secondary transport and non-specific ion loss throug

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